It might seem cool to have an interactive slide full of clickable links in your presentation. In yes, in a 1-on-1 meeting you could permit yourself the luxury of clicking back and forth through slides as you tell your story.
For a big audience, a linear story is much better. And when you need to click on a link in a slide, it is likely to be the exact same link/box/object every time. Why struggle with mouse pointers and try to hit that exact box when you can just click through the next slide that starts playing your video? The audience will not notice the difference.
